Defining multidrug-resistant tuberculosis: correlating GenoType MTBDR plus assay results with minimum inhibitory concentrations
نویسندگان
چکیده
منابع مشابه
GenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis Short title: GenoType MTBDR assay for drug-resistant tuberculosis
word count: 198 Text word count: 2998
متن کاملIntegrating drug concentrations and minimum inhibitory concentrations with Bayesian-dose optimisation for multidrug-resistant tuberculosis.
The problems of multidrug-resistant (MDR) tuberculosis (TB), extensively drug-resistant (XDR) TB, and even ‘‘totally drug-resistant’’ TB (a term that is still debated), have exposed two important clinical issues [1, 2]. The first issue involves figuring out a way to prevent these difficult-to-treat diseases. The second issue is treating patients with drug-resistant TB [3]. In the meantime even ...
متن کاملGenoType MTBDR assays for the diagnosis of multidrug-resistant tuberculosis: a meta-analysis.
The global extensively drug-resistant tuberculosis (TB) response plan calls for implementation of rapid tests to screen patients at risk of drug-resistant TB. Currently, two line probe assays exist, the INNO-LiPA(R)Rif.TB assay (Innogenetics, Ghent, Belgium) and the GenoType MTBDR assay (Hain LifeScience GmbH, Nehren, Germany). While LiPA studies have been reviewed, the accuracy of GenoType ass...
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D J Ulmasova1, G Uzakova2, M N Tillyashayhov3, L Turaev4, W van Gemert5, H Hoffmann6, M Zignol5, K Kremer7, T Gombogaram8, J Gadoev8, P du Cros9, N Muslimova4, A Jalolov2, A Dadu7, P de Colombani7, O Telnov10, A Slizkiy10, B Kholikulov1, M Dara7, D Falzon ([email protected])5 1. Republican DOTS Centre, Tashkent, Uzbekistan 2. Programme Implementation Unit, The Global Fund to Fight AIDS, TB and Ma...
متن کاملUse of Genotype MTBDRplus Assay for Diagnosis of Multidrug-Resistant Tuberculosis in Nepal
The main aims of this study were to study the patterns of mutations in rpoB, katG, and inhA genes in Mycobacterium tuberculosis strains isolated from patients from Nepal and to evaluate the performance of genotype MTBDRplus assay, taking conventional drug susceptibility testing as gold standard for diagnosis of MDR-TB. A total of 69 Mycobacterium tuberculosis strains isolated from 73 smear posi...
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ژورنال
عنوان ژورنال: Diagnostic Microbiology and Infectious Disease
سال: 2015
ISSN: 0732-8893
DOI: 10.1016/j.diagmicrobio.2015.01.009